Unlocking Sustainable Weight Loss: The Power of GLP-1 Agonists in Your Journey
- Chad Arterburn
- Dec 19, 2025
- 3 min read

In recent years, GLP-1 receptor agonists (often called GLP-1s) have revolutionized weight management and metabolic health. Medications like semaglutide (found in Ozempic and Wegovy) and tirzepatide (in Mounjaro and Zepbound) have helped millions achieve significant, life-changing weight loss. But what exactly are GLP-1s, and why are they so effective?
What Are GLP-1 Agonists?
GLP-1 agonists are medications that mimic the natural hormone glucagon-like peptide-1, produced in your gut after eating. This hormone plays key roles in:
Regulating blood sugar by stimulating insulin release and suppressing glucagon
Slowing gastric emptying to promote fullness
Reducing appetite by acting on brain centers that control hunger
Originally developed for type 2 diabetes, higher doses are now FDA-approved for chronic weight management in people with obesity or overweight with related conditions. When combined with diet and exercise, they deliver impressive results—typically 10-20% body weight loss over months to years.
Why GLP-1s Are a Game-Changer for Weight Loss and Health
Traditional weight loss often feels like an uphill battle because it fights against biology—hunger hormones, slowed metabolism, and cravings. GLP-1s address these root causes directly:
Powerful appetite suppression — Many users report reduced "food noise" and easier portion control without constant willpower struggles.
Significant, sustainable weight loss — Clinical trials show average losses of 15% with semaglutide and up to 20-22% with tirzepatide, far surpassing most diet-only approaches.
Broader health benefits — Beyond the scale, GLP-1s improve blood sugar control, lower blood pressure, enhance cholesterol profiles, reduce inflammation, and decrease risks for heart disease, kidney issues, sleep apnea, and fatty liver disease.
Even a 5-10% weight reduction can dramatically improve quality of life and longevity. For many, GLP-1s make achievable what once felt impossible.
Individual Responses: Semaglutide vs. Tirzepatide
While tirzepatide (a dual GLP-1/GIP agonist) generally leads to greater average weight loss than semaglutide (GLP-1 only), responses vary widely from person to person. Some individuals experience more substantial results and better tolerance with semaglutide, while others thrive on tirzepatide. Side effects like nausea, vomiting, or diarrhea can differ in intensity—some find one medication easier on the stomach than the other. This is why personalized medical guidance is crucial: your provider can help determine the best starting option and switch if needed for optimal results and comfort.
The Pros and Cons: A Balanced View
Like any powerful tool, GLP-1s have advantages and potential drawbacks.
Pros:
Clinically proven weight loss superior to most alternatives
Cardiovascular and metabolic protection (e.g., reduced risk of heart events and kidney progression)
Once-weekly injections for convenience
Helps build healthier habits by curbing cravings
Cons:
Common gastrointestinal side effects (nausea, vomiting, diarrhea, constipation)—usually mild and improve over time with slow dose escalation
Potential for muscle loss if not paired with protein-rich diet and strength training
Weight regains possible if discontinued without lifestyle maintenance
Cost can be high without insurance coverage, and in 2025, many insurers have implemented stricter criteria, prior authorizations, or exclusions for weight loss use (often limiting coverage to diabetes or specific comorbidities)
Rare serious risks (e.g., pancreatitis, gallbladder issues) that require monitoring
These cons are why expert guidance is essential—proper medical supervision minimizes risks and maximizes success.
Why Partnering with Experts Makes All the Difference
Navigating GLP-1s can be challenging with varying individual responses and increasingly strict insurance requirements for weight loss coverage. Working with a dedicated team like Stand Strong Lifestyles, Asher Med, & Dr. Broussard guidance and support, eliminates these obstacles by:
Providing physician assessments to match you with the right medication (semaglutide, tirzepatide, or alternatives) based on your unique biology and tolerance
Avoiding insurance and prior authorizations, while exploring affordable options to ensure access
Offering safe dose titration, ongoing monitoring, and adjustments to minimize side effects and optimize outcomes
Integrating access to science backed nutrition and fitness resources designed for Glp-1 users (to preserve muscle), and weekly check-ins for lifelong habits
Under professional oversight, side effects are manageable, benefits are amplified, and barriers like insurance hurdles are overcome—leading to safe, effective, and sustainable success. Many patients not only lose substantial weight but also gain energy, confidence, and improved overall health.
Ready to Transform Your Journey?
If you've struggled with weight despite diets and exercise, GLP-1 agonists could be the breakthrough you've been waiting for—tailored to your body and supported every step of the way. Paired with expert support from teams like Stand Strong Lifestyles, Asher Med, and Dr. Broussard, they offer a safe, effective path to lasting change, free from common access frustrations.
Don't settle for temporary fixes—embrace a science-backed approach that addresses biology while empowering sustainable habits. Contact us today and take the first step toward a stronger, healthier you. Your future self will thank you!
Have a blessed and healthy day,
Chad Arterburn
Stand Strong Lifestyles


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